Abstract Jackfruit is an exotic fruit present in the Northeast region of Brazil, presenting a great economic potential for the region because of the internal and external commercialization of its fruit. Its seed is rich in carbohydrates, protein, minerals and vitamins, and is an alternative source of starch and for food. Germination is an easily accessible, inexpensive technology for the production of sprouts, improving the bioavailability of nutrients in the seed for consumption, such as proteins and bioactive compounds. The objective of this work was to evaluate the chemical, physical and physicochemical parameters of fresh and germinated jackfruit seeds. The germination of jackfruit seeds increased the contents of water, proteins, ascorbic acid, phenolic compounds and total sugars, in addition to reducing the content of starch, lipids, tannins and the parameters of color, luminosity, red (+ a*) and yellow (+b*) intensities. In relation to the physical properties of the seed, there was an increase in the real specific mass and in the unit mass. For apparent specific mass there was a reduction. Seed germination provided an increase in the levels of magnesium, iron and sodium, consequently reducing potassium, phosphorus, calcium, zinc, copper and manganese.

Resumo A jaca é um fruto exótico presente na região Nordeste do Brasil, apresentando um grande potencial econômico para região em face da comercialização interna e externa do seu fruto. Sua semente é rica em carboidratos, proteína, minerais e vitaminas, constituindo fonte alternativa de amido para alimentação. A germinação é uma tecnologia barata de fácil acesso para produção de brotos, melhorando a biodisponibilidade de nutrientes na semente para o consumo, a exemplo das proteínas e compostos bioativos. O objetivo do trabalho foi avaliar os parâmetros químicos, físicos e físico-químicos das sementes de jaca in natura e germinadas. A germinação das sementes de jaca proporcionou o aumento nos teores de água, proteínas, ácido ascórbico, compostos fenólicos e açúcares totais, além de reduzir os conteúdo de amido, lipídios, taninos e os parâmetros de cor, a luminosidade, intensidade de vermelho (+a*) e de amarelo (+b*). Em relação às propriedades físicas da semente, ocorreu acréscimo na massa específica real e na massa unitária. Para massa específica aparente houve redução. A germinação das sementes proporcionou aumento nos teores de magnésio, ferro e sódio, consequentemente ocorrendo redução de potássio, fósforo, cálcio, zinco, cobre e manganês.

A enteroscopia de duplo balão é um método endoscópico que permite a visualização e biópsias de todo o intestino delgado. Os autores apresentam o caso clínico de um doente, de 55 anos, observado no Serviço de Urgência por dor abdominal e vómitos, apresentando nas análises uma anemia microcítica. Após a realização de vários exames auxiliares de diagnóstico, a tomografia computorizada abdominal mostrou um espessamento de uma ansa do intestino delgado. Realizou enteroscopia de duplo balão que permitiu o diagnóstico de linfoma não-Hodgkin B. Realizou quimioterapia com remissão completa.

Double-balloon enteroscopy allows endoscopic study and biopsies of the entire small bowel, allowing histological diagnosis throughout the procedure. The authors report a case of a 55 year-old man, observed in our emergency department with abdominal pain and vomiting. The blood tests has revealed a microcytic anemia. The abdominal computed tomography has shown a thick zone in the small bowel. A double-balloon enteroscopy was performed and it was diagnosed a B-cell Non-Hodgkin´s lymphoma. The patient was submitted to chemotherapy, with total remission.

A tetravalent rhesus-human reassortant rotavirus (RRV-TV) vaccine (4 x 10(4) plaque-forming units/dose) was evaluated for safety, immunogenicity and efficacy in a prospective, randomized, double-blind, placebo-controlled trial involving 540 Brazilian infants. Doses of vaccine or placebo were given at ages, 1, 3 and 5 months. No significant differences were noted in the occurrence of diarrhoea or vomiting in vaccine and placebo recipients following each dose. Low-grade fever occurred on days 35 in 23% of vaccinees after the first dose, but not after the second or third doses of vaccine. An IgA antibody response to rhesus rotavirus (RRV) occurred in 58% of vaccinees and 33% of placebo recipients. Neutralizing antibody responses to individual serotypes did not exceed 20% when measured by fluorescent focus reduction, but exceeded 40% when assayed by plaque reduction neutralization. There were 91 cases of rotavirus diarrhoea among the 3-dose (vaccine or placebo) recipients during two years of follow-up, 36 of them among children given the vaccine. Overall vaccine efficacy was 8% (P = 0.005) against any diarrhoea and 35% (P = 0.03) against any rotavirus diarrhoea. Protection during the first year of follow-up, when G serotype 1 rotavirus predominated, was 57% (P = 0.008), but fell to 12% in the second year. Similar results were obtained when analysis was restricted to episodes in which rotavirus was the only identified pathogen. There was a tendency for enhanced protection by vaccine against illness associated with an average of 6 or more stools per day. These results are sufficiently encouraging to warrant further studies of this vaccine in developing countries using a higher dosage in an attempt to improve its immunogenicity and efficacy.

Se evaluó la inocuidad, inmunogenicidad y eficacia de una vacuna tetravalente obtenida por recombinación genética de rotavirus aislados de monos rhesus y seres humanos (RRV-TV) (4 x 10(4) unidades formadoras de placas por dosis) en un ensayo prospectivo, aleatorio, a doble ciego y controlado con placebo que se efectuó con 540 lactantes brasileños. Se administraron dosis de vacuna o de placebo a la edad de 1, 3 y 5 meses. No se observaron diferencias significativas en la frecuencia de diarrea o vómito en los bebés de ninguno de los dos grupos después de administrar la dosis correspondiente. De 2 a 3% de los vacunados tuvieron fiebre baja los días tercero a quinto después de recibir la primera dosis, pero no después de las dosis segunda o tercera. Se observó una respuesta de anticuerpos del tipo IgA al rotavirus aislado de monos rhesus (RRV) en 58% de los vacunados y en 33% de quienes recibieron placebo. La respuesta de anticuerpos neutralizantes a cada serotipo no pasó de 20% cuando se determinó con la prueba de reducción de focos de fluorescencia, pero fue superior a 40% al medirse con la prueba de neutralización a base de reducción de placas. Se presentaron 91 casos de diarrea causada por rotavirus entre los niños que recibieron las tres dosis (de vacuna o de placebo) durante un seguimiento de 2 años, 36 de ellos en los niños vacunados. La eficacia general de la vacuna fue de 8% (P = 0,005) contra toda clase de diarrea y de 35% (P = 0,03) contra la diarrea causada por rotavirus. La protección durante el primer año de seguimiento, cuando predominó el rotavirus G del serotipo 1, fue de 57% (P = 0,008), pero se redujo a 12% en el segundo año. Se obtuvieron resultados similares al restringir el análisis a episodios en que el rotavirus fue el único agente patógeno identificado. Se observó en la vacuna una mayor tendencia a proteger contra casos de enfermedad con un promedio de seis o más deposiciones diarias. Estos resultados son lo suficientemente alentadores para justificar que en países en desarrollo se hagan otros estudios de esta vacuna con una dosis mayor para tratar de mejorar su inmunogenicidad y eficacia.

Os cultivares de soja 'paraná', 'viçoja' e 'santa-rosa', a linhagem IAC 73-223 e as introduções PI 171451 e PI 229358 foram testados em condições de campo para avaliar a resistência a percevejos. Ocorreram nesse campo experimental apenas as espécies de percevejos pentatomídios Nezara viridula L. e Piezodorus guildinii Westw. em iguais proporções. A linhagem IAC 73-228 teve a menor porcentagem de grãos danificados (48,1%) na metade superior da planta e as introduções PI 171451 (71,1%) e PI 229358 (79,1%) apresentaram porcentagem intermediária de grãos danificados. O cultivar 'paraná' foi o mais danificado, com 96,87%. Houve correlação significativa entre porcentagem de dano e porcentagem de plantas com retenção foliar (hastes verdes) por ocasião da colheita. Houve correlação positiva entre tamanho dos grãos e dano dos percevejos. O dano foi maior na parte superior das plantas que na inferior.

The soybean cultivars Paraná. Viçoja and Santa Rosa, the line IAC 73-228 and the introductions PI 171451 and PI 229358,e were tsted in Campinas, State of São Paulo, Brazil, in relation to the stink bugs Nezara viridula L. and Piezodorus guildinii Westw. The line IAC 73-228 had the least percentage of damaged seed (48,l%) in the superior half of the plant, whereas Paraná had the highest (96,8%). The introductions PI-171451 (71,1%) and PI 229358 (79,1%) had intermediate degrees of damaged seeds. This difference in damaged seeds could be due to actual resistance to the stink bugs, to resistance to Nematospora coryli transmitted by these insects or due to host evasion. It has been observed by DAUGHERTY et al. (1964) and LINK & COSTA (1974), that varieties with shorter period from flowering to harvest are less damaged by stink bugs and this would be a case of pseudo resistance called host evasion according to PAINTER (1951). There was a high positive correlation between percentage of seeds damaged and green stems at harvest. This feature could be used for field selection against these insects. There was positive significant correlation between damage and seed size. The seed size may be linked in some way to susceptibility to stink bugs. The damage was higher in the superior half of the plants than in the inferior.